Nectin-4 is an important target that has been shown to be available as a treatment for locally advanced and advanced bladder cancer. Based on this, Padcev (enfortumab-vedotin-ejfv), the first ADC drug (antibody-coupled drug) for uroepithelial carcinoma, has also received accelerated FDA approval for the treatment of locally advanced or advanced bladder cancer in patients who have previously received immune checkpoint inhibitors (PD-L1, PD-1) and platinum-containing chemotherapy before surgery (neoadjuvant therapy) or after surgery (adjuvant therapy). Adult patients with advanced or late-stage uroepithelial carcinoma (a common type of bladder cancer).
"Cancer"
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Disease
How effective is immunotherapy for gastric cancer? What other treatment options are available for gastric cancer?
Stomach cancer can cause abnormal symptoms in the digestive system, even vomiting blood and black stools, so it should be treated promptly after having stomach cancer
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Medical
UK Launches First Clinical Trial Of Proton Beam Therapy For Breast Cancer To Help Patients Reduce The Risk Of Heart Problems Caused By Radiotherapy
The clinical trial (PARABLE) will take place at 22 sites across the UK and is planned to recruit 192 patients at higher risk of developing heart problems. the PARABLE trial is led by researchers from the Royal Marsden Hospital, the University of Cambridge, and the Institute of Cancer Research (ICR) UK, and is managed by the Clinical Trials and Statistics Unit, funded by Cancer Research UK, at the Institute of Cancer Research (ICR). was conducted.
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Disease
Can i Still Have Surgery For Pancreatic Cancer With Portal Vein Invasion? What Are The Symptoms Of Pancreatic Cancer And How Can It Be Detected?
Pancreatic cancer is a very complex and common tumour of the pancreas, and the malignancy of this disease is relatively high.
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Medical
New Targeted Radiotherapy For "Laser-Like" Precision Treatment Of Refractory Prostate Cancer With Fewer Side Effects!
Prostate cancer, which has been increasing in incidence worldwide in recent years, is now a more common cancer among Japanese men. Often, patients with prostate cancer have a poor prognosis and poor survival once they have developed multiple recurrent metastases after treatment with hormones and are difficult to treat with conventional radiotherapy.
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The FDA has granted accelerated approval to Adagrasib for the treatment of patients with KRAS G12C mutations in non-small cell lung cancer. In the trial, the drug resulted in disease control in 80% of patients, of which, 43% had substantial tumour shrinkage.
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A new generation of oral selective estrogen receptor degrader, elastostat, has shown promise in clinical studies over standard second-line treatments such as fulvestrant for the treatment of patients with metastatic hormone receptor-positive breast cancer.
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Apparatus
Acs Med. Chem. Lett.| Protac-Targeted Jak2 Protein Kinase: a New Approach To Cancer Therapy
A new approach to cancer treatment!
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Medical
Neoadjuvant Chemotherapy Reduces Colon Cancer Recurrence Rate By 28%, With Fewer Post-Operative Complications, Study Shows
Preoperative oxaliplatin-fluoropyrimidine chemotherapy given to colon cancer patients did not increase the risk of perioperative complications in colon cancer patients and did reduce postoperative recurrence rates, according to the results of the international phase 3/4 FOxTROT trial.
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Medical
New Strategies For Cancer Vaccines: Transforming Cancer Cells So They Can Become Cancer-Fighters Is Not Far Away!
In recent years, scientists have begun to look at "transforming" cancer cells from life-threatening bad actors to help fight cancer.