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It is estimated that ninety percent of deaths from breast cancer are caused by complications from metastasis, so how to effectively stop breast cancer metastasis has long been a hot topic in cancer research.

Some people have cold symptoms such as cold hands and feet, unformed stools, and a fear of cold and warmth in the small of the abdomen when they are on fire.

Founded in 1811, Massachusetts General Hospital is the earliest and largest teaching affiliated hospital of Harvard Medical School, and one of the three oldest hospitals in the United States. In 2012, hospitals in the United States ranked first (US News&World Report). In 1846, the first anesthetic operation was performed in human history, and X-ray was first used in clinical practice in 1896. Massachusetts General Hospital dominates the largest hospital based research project in the United States, with an annual research funding of more than 600 million dollars. So far, 13 Nobel laureates have been produced

The Affiliated Hospital of the Medical Department of the University of Tokyo originated from the first vaccination institute (vaccinia vaccination institute) opened in present-day Tokyo in the late Edo era, and has been leading the development of Japanese medicine and medical industry for more than 150 years. Adhering to the philosophy of "devoting to the development of clinical medicine and the training of medical talents to provide the best medical treatment for each patient", the hospital carries out its daily work with the following purposes: (1) practice medical treatment that respects the wishes of patients; (2) Provide safe medical care; (3) Develop highly advanced medical treatment; (4) Cultivate excellent medical talents.

Toronto General Hospital is the main teaching hospital in Toronto, Canada, and one of the five major hospitals of the Canadian University Health Network. Toronto General Hospital is the largest organ transplantation center in Canada and even North America, which can transplant heart, lung, kidney, liver, pancreas, small intestine and other organs for patients. Toronto General Hospital is world-famous for Peter Monk Heart Center, which is considered as the "global leader" in open heart surgery and cardiovascular health. In addition, the Toronto Institute is also the research institution with the most sufficient research funds in Canada, and has been rated as the first medical research institution in Canada by the well-known consulting company Research Infosource for nine consecutive years. The Toronto General Hospital, which is known as "the best hospital in Canada", deserves its name.

Singapore General Hospital (SGH) is the first and largest hospital in Singapore. It provides affordable specialist care for patients, training for doctors and other healthcare professionals, and conducts research to bring better care to its patients. 

Although the Mayo Clinic in the United States is called a "clinic", it is actually a comprehensive medical center with a long history, the world's first and largest comprehensive, non-profit, group medical institution, and a well deserved medical system brand in the world's medical field.

The University Hospital of Lausanne is one of the five major university hospitals in Switzerland, as famous as Geneva, Bern, Basel and Zurich. CHUV has 16 clinical and medical technology departments and numerous service projects, and is famous for its academic achievements in medical care, research and teaching.

Founded in 1948, Sheba Medical Center is the largest and most comprehensive medical center in Israel and even in the Middle East. It is also the first medical center in Israel to provide patients with artificial hearts and the first test tube baby birth. This tertiary hospital affiliated to Tel Aviv University involves almost all specialties. Its obstetrics, gynecology, pediatrics, neonatology, rehabilitation and other specialties enjoy high reputation internationally, It provides services to more than 1 million patients every year,More than 25% of Israel's medical clinical research is conducted in the Sheba Medical Center, which also cooperates with almost all Israeli medical institutions to provide medical education and promote the future development of the medical profession.

The University of Chicago Medical Center is one of the nation's leading academic medical institutions, home to the University of Chicago, which has been among the top 10 universities in the world for many years, has produced 92 Nobel Prize winners, including 12 in physiology or medicine, and has been at the forefront of global healthcare.