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Founded in 1948, Sheba Medical Center is the largest and most comprehensive medical center in Israel and even in the Middle East. It is also the first medical center in Israel to provide patients with artificial hearts and the first test tube baby birth. This tertiary hospital affiliated to Tel Aviv University involves almost all specialties. Its obstetrics, gynecology, pediatrics, neonatology, rehabilitation and other specialties enjoy high reputation internationally, It provides services to more than 1 million patients every year,More than 25% of Israel's medical clinical research is conducted in the Sheba Medical Center, which also cooperates with almost all Israeli medical institutions to provide medical education and promote the future development of the medical profession.

The University of Chicago Medical Center is one of the nation's leading academic medical institutions, home to the University of Chicago, which has been among the top 10 universities in the world for many years, has produced 92 Nobel Prize winners, including 12 in physiology or medicine, and has been at the forefront of global healthcare.

It is estimated that ninety percent of deaths from breast cancer are caused by complications from metastasis, so how to effectively stop breast cancer metastasis has long been a hot topic in cancer research.